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Changes of Tear Film and Ocular Surface in Diabetes Mellitus
Korean Journal of Ophthalmology ; : 168-174, 2004.
Article in English | WPRIM | ID: wpr-31478
ABSTRACT
This study was performed to investigate the changes of tear film and ocular surface in diabetic patients, as well as the ocular and systemic factors related to these changes. We assessed the scoring of keratoepitheliopathy, corneal sensitivity test, tear film break-up time (BUT), Schirmer test, and conjunctival impression cytology in 94 eyes of 47 patients with noninsulin-dependent diabetes mellitus and in 60 eyes of 30 normal subjects. The degree of keratoepitheliopathy was severe, and the corneal sensitivity, BUT, and tear secretion were significantly reduced in the diabetic patients. Conjunctival impression cytology showed a higher grade of conjunctival squamous metaplasia and lower goblet cell density in the diabetic patients. All parameters were related to the status of metabolic control, diabetic neuropathy, and stage of diabetic retinopathy. We think that diabetic patients with poor metabolic control, neuropathy, and advanced stage of retinopathy should be examined for tear film and ocular surface changes.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Tears / Comparative Study / Risk Factors / Epithelium, Corneal / Corneal Diseases / Goblet Cells / Diabetes Complications Type of study: Etiology study / Risk factors Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Korean Journal of Ophthalmology Year: 2004 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Tears / Comparative Study / Risk Factors / Epithelium, Corneal / Corneal Diseases / Goblet Cells / Diabetes Complications Type of study: Etiology study / Risk factors Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Korean Journal of Ophthalmology Year: 2004 Type: Article