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Desmoplastic small round cell tumor: report of 2 cases / 中华外科杂志
Zhonghua Wai Ke Za Zhi ; (12): 214-215, 2002.
Article in Zh | WPRIM | ID: wpr-314895
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To recognize the characteristics of desmoplastic small round cell tumor (DSRCT) and improve the standard of diagnosis.</p><p><b>METHODS</b>We retrospectively reviewed the clinical data on the treatment of 2 patients with DSRCT in terms of their conditions, tissue sources, pathologic characteristics, immunohistochemical methods, clinical manifestation, diagnosis, treatment and prognosis.</p><p><b>RESULTS</b>Clinical manifestations were complicated. The 2 patients were mis diagnosed before operation. Their tumors consisted of irregular nests of small and round cells, with nuclear hyperchromatism and scant cytoplasm embedded in a plenty of fibrous connective tissues. The edge of the nest was clear, with different sizes and shapes. Immunohistochemically, the 2 patients were positive for CK or EMA, NSE, des and vim of the epithelium, nerve, muscle and interstitial. They died 9 months after operation.</p><p><b>CONCLUSIONS</b>The tumor may occur in the abdomen, pelvic cavity and other sites, with different clinical manifestations. Routine examination should be replaced by immunohistochemical test for correct diagnosis of the tumor. Prognosis of most patients is not good.</p>
Subject(s)
Full text: 1 Index: WPRIM Main subject: Immunohistochemistry / Retrospective Studies / Carcinoma, Small Cell / Diagnosis / Neoplasms, Connective Tissue Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Female / Humans / Male Language: Zh Journal: Zhonghua Wai Ke Za Zhi Year: 2002 Type: Article
Full text: 1 Index: WPRIM Main subject: Immunohistochemistry / Retrospective Studies / Carcinoma, Small Cell / Diagnosis / Neoplasms, Connective Tissue Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adolescent / Female / Humans / Male Language: Zh Journal: Zhonghua Wai Ke Za Zhi Year: 2002 Type: Article