Resistance to beta-lactam antibiotics in hospital health workers

ABSTRACT

Study on 589 nurses and midwives who have been working at least 2 years at hospitals in Hanoi, they were interviewed about the time of occupational contact to antibiotics, the allergic history with beta-lactam antibiotics. All participants were done skin prick test with benzyl penicillin G and ampicillin. Total serum IgE and reaction of mastocyte transform in the subjects who had allergic history to beta-lactam antibiotic. Results showed that the allergic prevalence to beta-lactam antibiotics is very high (9.3%). The occupational factors have clearly affected to the allergy including proportion of occupation ages, family allergic history, and persons who used to suffer from the diseases of allergy and immunology have the allergic risk to beta-lactam antibiotics.