Bioactive constituents from whole herbs of Vernonia cinerea (II) / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2765-2767, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-315367
ABSTRACT
<p><b>OBJECTIVE</b>To study the constituents of the whole herbs of Vernonia cinerea by bio-activity guided isolation with PC-12 model.</p><p><b>METHOD</b>The constituents were separated by column chromatography and the structures were elucidated by spectroscopic methods.</p><p><b>RESULT</b>Ten compounds were identified to be (-)-clovane-2,9-diol (1), caryolane-1,9beta-diol (2), apigenin (3), chrysoeriol (4), luteolin (5), thermopsoside (6), luteolin-7-O-beta-D-glucoside (7), quercetin(8), apigenin-4'-O-beta-D-glucoside (9), hyperin (10), beta-amyrin aceate (11), lupeol acetate (12).</p><p><b>CONCLUSION</b>Compounds 1, 2, 6 and 10 were isolated from this genus for the first time.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drugs, Chinese Herbal
/
Chemistry
/
PC12 Cells
/
Vernonia
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2009
Type:
Article
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