Value of blood inflammatory markers in the diagnosis of acute appendicitis in children / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1154-1156, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-315514
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of serum inflammatory markers in the diagnosis of acute appendicitis (AA) in children.</p><p><b>METHODS</b>Blood samples were collected from 51 children with AA and 16 children with nonsurgical abdominal pain (NSAP) to examine white blood cell count (WBC), serum C-reactive protein (CRP), interleukin-6, and tumor necrosis factor-α (TNF-α).</p><p><b>RESULTS</b>WBC count, CRP, IL-6 and TNF-α increased significantly in children with severe AA (phlegmonous or gangrenous, and perforated appendicitis). ROC curves showed that IL-6 or TNF-α had a greater contribution than WBC count to the diagnosis of severe appendicitis.</p><p><b>CONCLUSION</b>IL-6 and TNF-α can provide complementary information to assist the clinical decision of emergency operation for children with AA.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Appendicitis
/
Blood
/
C-Reactive Protein
/
Biomarkers
/
Interleukin-6
/
Tumor Necrosis Factor-alpha
/
Lymphocyte Count
/
Diagnosis
/
Inflammation
/
Metabolism
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2012
Type:
Article
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