Quantitative assessment of left ventricular systolic dyssynchrony in relation to systolic function by real-time three-dimensional echocardiography-derived regional systolic dyssynchrony index in chronic heart failure patients / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1122-1126, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-315522
ABSTRACT
<p><b>OBJECTIVE</b>To quantitatively assess the left ventricular systolic dyssynchrony in patients with chronic heart failure based on the regional systolic dyssynchrony index (R-SDI) derived from real-time three-dimensional echocardiography (RT-3DE), and investigate the relation between R-SDI and the left ventricular systolic function.</p><p><b>METHODS</b>Forty-two patients with chronic heart failure (LVEF<50%) were classified into severe dysfunction group (group A, LVEF<40%) and mild dysfunction group (group B, LVEF≥40%), with 33 healthy subjects as the control group (LVEF>50%). RT-3DE was performed for each subject to obtain the left volume-time curves and the 16, 12, and 6 segment R-SDI. The value of R-SDI in assessing left ventricular systolic dyssynchrony and its correlation with LVEF were analyzed.</p><p><b>RESULTS</b>The 16, 12, and 6R-SDI were significantly higher in the chronic heart failure group than in the control group (P<0.01). The R-SDI of group A was significantly greater than those of group B in the chronic heart failure patients (P<0.01), and 16R-SDI, 12R-SDI, and 6R-SDI were inversely correlated with LVEF of the patients (r=-0.843, -0.840, and -0.841, respectively, P<0.01).</p><p><b>CONCLUSIONS</b>R-SDI can be used to assess the left ventricular mechanic systolic dyssynchrony, and the degree of the dyssynchrony is inversely correlated with LVEF. RT-3DE can serve as a valuable modality for quantitative evaluation of left ventricular dyssynchrony in chronic heart failure patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Systole
/
Diagnostic Imaging
/
Case-Control Studies
/
Chronic Disease
/
Ventricular Function, Left
/
Ventricular Dysfunction, Left
/
Echocardiography, Three-Dimensional
/
Heart Failure
/
Heart Ventricles
/
Methods
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2012
Type:
Article
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