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Chemical constituents from red alga Corallina pilulifera / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 1787-1790, 2006.
Article in Chinese | WPRIM | ID: wpr-315958
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of red alga Corallina pilulifera.</p><p><b>METHOD</b>Compounds were isolated by normal phase silica gel and Sephadex LH - 20 gel column chromatography, reverse phase HPLC and recrystallization. Their structures were elucidated by spectroscopic methods including MS, 1H-NMR, 13C-NMR, HSQC, HMBC. Cytotoxicity of the compounds was screened by using standard MTT method.</p><p><b>RESULT</b>Seven compounds were isolated from red alga C. pilulifera, their structures were identified as (E) -phytol epoxide (1), phytenal (2), phytol (3), dehydrovomifoliol (4), loliolide (5), 3beta-hydroxy-5alpha, 6alpha-epoxy-7-megastigmene-9-one (6), 4-hydroxybenzaldehyde (7).</p><p><b>CONCLUSION</b>All of the compounds were obtained from this species for the first time. These compounds were inactive (IC50 > 10 microg x mL(-1)) in the MTT assay.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Phytol / Benzaldehydes / Benzofurans / Chemistry / Cell Line, Tumor / Rhodophyta Limits: Humans Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Phytol / Benzaldehydes / Benzofurans / Chemistry / Cell Line, Tumor / Rhodophyta Limits: Humans Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2006 Type: Article