Chemical constituents from red alga Corallina pilulifera / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1787-1790, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-315958
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of red alga Corallina pilulifera.</p><p><b>METHOD</b>Compounds were isolated by normal phase silica gel and Sephadex LH - 20 gel column chromatography, reverse phase HPLC and recrystallization. Their structures were elucidated by spectroscopic methods including MS, 1H-NMR, 13C-NMR, HSQC, HMBC. Cytotoxicity of the compounds was screened by using standard MTT method.</p><p><b>RESULT</b>Seven compounds were isolated from red alga C. pilulifera, their structures were identified as (E) -phytol epoxide (1), phytenal (2), phytol (3), dehydrovomifoliol (4), loliolide (5), 3beta-hydroxy-5alpha, 6alpha-epoxy-7-megastigmene-9-one (6), 4-hydroxybenzaldehyde (7).</p><p><b>CONCLUSION</b>All of the compounds were obtained from this species for the first time. These compounds were inactive (IC50 > 10 microg x mL(-1)) in the MTT assay.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Phytol
/
Benzaldehydes
/
Benzofurans
/
Chemistry
/
Cell Line, Tumor
/
Rhodophyta
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2006
Type:
Article
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