Study on anti-tumor effect of medicinal fungi Phellinus igniarius extracts / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the inhibiting effect of medicinal fungi Phellinus igniarius extracts on S180 tumor and the immunoregulation effect on the S180-induced tumor mice.</p><p><b>METHOD</b>S180 mice were orally given 100, 200, 400 mg x kg(-1) dosage of P. igniarius extracts, then the inhibition grow effect, spleen index, and thyme index were measured.</p><p><b>RESULT</b>Medicinal fungi P. igniarius extracts can increase the spleen index and thyme index and the inhibiting tumor rate was 31.88%, 46.25%, 53.13%, respectively. Also, medicinal fungi P. igniarius extracts can prolong life in mice.</p><p><b>CONCLUSION</b>The medicinal fungi P. igniarius extracts show obviously anti-tumor effect and immunoregulation effect.</p>