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Liver transplantation for the treatment of hepatocellular carcinoma / 中华肿瘤杂志
Chinese Journal of Oncology ; (12): 628-631, 2006.
Article in Chinese | WPRIM | ID: wpr-316341
ABSTRACT
<p><b>OBJECTIVE</b>To retrospectively evaluate the clinical outcomes of liver transplantation for patients with hepatocellular carcinoma (HCC).</p><p><b>METHODS</b>The clinical data of 88 consecutive HCC patients who underwent orthotopic liver transplantation between 2002. 4 and 2004. 7 were retrospectively reviewed. HCC stage of those patients were defined according to the pTNM classification system of UICC. All patients were followed up for more than 12 months after liver transplantation. The recurrence and overall survival rate were evaluated by univariate and multivariate analysis with SAS software.</p><p><b>RESULTS</b>The cumulative 1-year recurrence rate of stage I, II, III and IV after liver transplantation was 0%, 4.8%, 40.0% and 71.3%, respectively (P < 0.01). The cumulative 1-year overall survival rate of stage I, II, III and IV was 100%, 95.2%, 71.5% and 41.7%, respectively (P < 0.01).</p><p><b>CONCLUSION</b>Liver transplantation may be suitable for stage I or II hepatocellular cancer patients and improve their prognosis, while it is not suitable for stage IV HCC patients.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / General Surgery / Survival Analysis / Retrospective Studies / Follow-Up Studies / Liver Transplantation / Treatment Outcome / Carcinoma, Hepatocellular / Liver Neoplasms / Neoplasm Recurrence, Local Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Oncology Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / General Surgery / Survival Analysis / Retrospective Studies / Follow-Up Studies / Liver Transplantation / Treatment Outcome / Carcinoma, Hepatocellular / Liver Neoplasms / Neoplasm Recurrence, Local Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Chinese Journal of Oncology Year: 2006 Type: Article