Meta-analysis of safety and efficacy on exercise rehabilitation in coronary heart disease patients post revascularization procedure / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 334-340, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-316463
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the safety and efficacy of exercise rehabilitation in coronary heart disease patients post reascularization procedure.</p><p><b>METHOD</b>We searched the Cochrane Central Register of Controlled Trials (CCRCT), Pubmed, Wanfang, CNKI, CBM and VIP database for randomized controlled trials (RCTs) on exercise rehabilitation for patients with coronary artery disease post percutaneous coronary intervention revascularization or coronary artery bypass grafting. Quality assessment and data collection were conducted by two reviewers independently. The data were analyzed by Review Manager 5.0.</p><p><b>RESULTS</b>A total of 3 474 patients from 16 RCTs were included in this meta-analysis and patients were divided into exercise rehabilitation group (n = 1 425) and control group (n = 2 049). Meta-analysis results showed mortality rate was similar between the two groups (OR = 0.81, 95%CI 0.38-1.69, P > 0.05) and the incidence of major cardiovascular events rate (OR = 0.40, 95%CI 0.24-0.65, P < 0.01) and heart rate [mean difference (MD) = -2.82, 95%CI -4.72--0.92, P < 0.01] were significantly lower while LVEF (MD = 2.24, 95%CI 0.18-4.31, P < 0.05), the exercise metabolic equivalent (MD = 0.94, 95%CI 0.43-1.44, P < 0.01) , anaerobic threshold (MD = 1.83, 95%CI 0.67-3.00, P < 0.01) , and maximum oxygen consumption (MD = 3.22, 95%CI 2.42-4.03, P < 0.01) were significantly higher in exercise rehabilitation group than in control group.</p><p><b>CONCLUSION</b>Exercise rehabilitation does not increase the risk of mortality in patients of coronary heart disease after revascularization and can effectively reduce major cardiovascular events.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rehabilitation
/
General Surgery
/
Coronary Artery Bypass
/
Treatment Outcome
/
Coronary Disease
/
Exercise Therapy
/
Percutaneous Coronary Intervention
Type of study:
Controlled clinical trial
/
Systematic reviews
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Cardiology
Year:
2014
Type:
Article
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