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Research progress of acute coagulopathy of trauma-shock / 中华创伤杂志(英文版)
Chinese Journal of Traumatology ; (6): 95-97, 2015.
Article in English | WPRIM | ID: wpr-316843
ABSTRACT
Acute coagulopathy of trauma-shock (ACoTS) occurs in 25% of patients with severe trauma in the early phase, and the mortality of those patients is four-fold higher than patients without coagulopathy. The pathophysiology of this complicated phenomenon has been focused on in recent years. Tissue injury and hypoperfusion, activated protein C and Complements play important roles in the early phase after trauma. While the use of blood products, hypothermia, acidosis and inflammation are the main mechanism in late phase. Supplementing coagulation factors and platelets to improve ACoTS are inefficient. Only positive resuscitation from shock and improving tissue hypoperfusion have expected benefits.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Shock, Traumatic / Blood Coagulation Disorders / Complement System Proteins / Protein C / Disseminated Intravascular Coagulation / Hypothermia / Inflammation Limits: Humans Language: English Journal: Chinese Journal of Traumatology Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physiology / Shock, Traumatic / Blood Coagulation Disorders / Complement System Proteins / Protein C / Disseminated Intravascular Coagulation / Hypothermia / Inflammation Limits: Humans Language: English Journal: Chinese Journal of Traumatology Year: 2015 Type: Article