The study of the sensitive and specificity on HBV DNA replication by HBV-lP detecting / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 68-70, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-316962
ABSTRACT
<p><b>OBJECTIVE</b>To detect HBV-LP and HBV DNA of the patients with hepatitis B, and to study the sensitive and specificity of HBV-LP detecting and its evaluate on for clinical application.</p><p><b>METHODS</b>The ELISA was used for HBV-LP detecting and RT-PCR for HBV DNA detecting.</p><p><b>RESULTS</b>The sensitive and specificity of HBV-LP and HBV DNA were 64.89%, 99.68%, 60.63% and 100% respectively (P > 0.05); +LR, -LR were 202.78, 60.63, 0.3522 and 0.3937, and there were significance between +LR of the detecting (P < 0.005).</p><p><b>CONCLUSION</b>The sensitive and specificity of HBV-LP and HBV DNA detecting are considerable, +LR of HBV-LP are higher comparing HBV DNA. The HBV-LP is better serology index for detecting replication of HBV DNA.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virology
/
Blood
/
Enzyme-Linked Immunosorbent Assay
/
Viral Envelope Proteins
/
Hepatitis B virus
/
Sensitivity and Specificity
/
Reverse Transcriptase Polymerase Chain Reaction
/
Diagnosis
/
DNA Replication
/
Genetics
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2010
Type:
Article
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