Development of new methods for the diagnosis of nasopharyngeal carcinoma / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 65-67, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-316963
ABSTRACT
<p><b>OBJECTIVE</b>Development of new methods, ELISA and immunostrip test, for the diagnosis of nasopharyngeal carcinoma.</p><p><b>METHODS</b>The engineering purified antigens coat plate or absorb on nitrocellulose filter. The plate and diagnostic strips carrying antigens were used for detection of IgG antibody in the sera from nasopharyngeal carcinoma patients and outpatients patients.</p><p><b>RESULTS</b>127 cases sera from nasopharyngeal carcinoma patients were parallel detected TK/IgG antibody by ELISA and immunostrips. The TK/IgG antibody are all positive in the 127 cases of nasopharyngeal carcinoma patients. 55 cases show positive by ELISA, 58 cases positive by immunostrips in 247cases sera from outpatient. The antibody positive rate to early antigen p54 lower then to TK. Conclusion ELISA and imuunostrips are sensitive and specific means for detection of the IgG antibody to TK of EBV and the diagnosis of nasopharyngeal carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reagent Strips
/
Thymidine Kinase
/
Viral Proteins
/
Virology
/
Blood
/
Immunoglobulin G
/
Enzyme-Linked Immunosorbent Assay
/
Carcinoma
/
Nasopharyngeal Neoplasms
/
Herpesvirus 4, Human
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2010
Type:
Article
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