Role of urinary basic fibroblast growth factor in differentiating hemangiomas from vascular malformation / 中华外科杂志
Chinese Journal of Surgery
;
(12): 186-188, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-317185
ABSTRACT
<p><b>OBJECTIVE</b>To investigate a novel method to differentiate hemangioma from vascular malformation, to stage hemangiomas and to monitor the efficacy of management for hemangioma.</p><p><b>METHODS</b>The urinary basic fibroblast growth factor (bFGF) concentration of 144 cases (including 69 cases of proliferating hemangiomas, 41 cases of involuting hemangiomas, 23 cases of vascular malformations and 11 negative controls) was examined using enzyme linked immunosorbent assay (ELISA).</p><p><b>RESULTS</b>The differences of urinary bFGF concentration among proliferating hemangiomas, involuting hemangiomas, vascular malformations and negative control were all significant, while the differences between the latter three groups were not significant.</p><p><b>CONCLUSIONS</b>Our findings suggest that examination of urinary bFGF concentration using ELISA technique is helpful in differentiating hemangioma from vascular malformation, staging hemangiomas and dynamically monitoring the efficacy of treatment for hemangiomas. Our results probably shed new light on the potential pathogenesis of hemangiomas and vascular malformation.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arteriovenous Malformations
/
Urine
/
Fibroblast Growth Factor 2
/
Diagnosis
/
Diagnosis, Differential
/
Hemangioma
Type of study:
Diagnostic study
Limits:
Child, preschool
/
Humans
/
Infant
/
Infant, Newborn
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2006
Type:
Article
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