Relationship between the growth rate of corpus callosum and neuromotor delay in premature infants / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 701-704, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-317353
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between the growth rate of the corpus callosum and neurological motor development in premature infants.</p><p><b>METHODS</b>Fifty infants whose gestational ages were less than 34 weeks and who were admitted to the neonatal intensive care unit from March 2007 to August 2007 were enrolled. From 0 to 6 weeks of postnatal age, the sagittal midline cranial sonography via anterior fontanel was performed, once weekly. The length and the morphology of the corpus callosum were measured. The 52-neuromotor examinations were performed at 3 months of corrected gestational age.</p><p><b>RESULTS</b>The mean length of the corpus callosum was 39.16 mm at birth. The mean growth rate of the corpus callosum during the first 6 weeks of life was 1.05 mm/week. Fourteen infants showed abnormal neuromotor development and 36 had normal-neuromotor function at 3 months of corrected gestational age. A decreased growth rate of the corpus callosum was observed in the abnormal nervimotion group between 2 and 3 weeks (0.68 mm/week vs 1.17 mm/week) and between 4 and 5 weeks (0.86 mm/week vs 1.12 mm/week) after birth compared with that in normal nervimotion group (p<0.05). The total growth rate of the corpus callosum from 2 to 6 weeks after birth in the abnormal nervimotion group was also lower than that in the normal nervimotion group (0.91 mm/week vs 1.15 mm/week; p<0.01).</p><p><b>CONCLUSIONS</b>A neuromotor delay at 3 months of corrected gestational age may be associated with the decreased growth rate of the corpus callosum between 2 and 6 weeks of life in premature infants.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Infant, Premature
/
Diagnostic Imaging
/
Developmental Disabilities
/
Ultrasonography
/
Corpus Callosum
/
Motor Activity
Type of study:
Diagnostic study
Limits:
Humans
/
Infant
/
Infant, Newborn
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2008
Type:
Article
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