Epidemiological characteristics of major abnormal electrocardiogram in adults from Shanghai / 中华流行病学杂志

ABSTRACT

Objective To understand the prevalence,characteristics and risk factors of major abnormal electrocardiogram (MA-ECG) in adults living in Shanghai.Methods The cross-sectional dataset of prevalence survey on diabetes and metabolic syndrome in adults,aged 20-74 years,from Shanghai,in 2007-2008,was analyzed.Demographic information,personal and,family histories of diseases were collected.Physical examination and laboratory tests were done.Subjects underwent examination on resting 12-leads electrocardiogram (ECG),ECG records were coded according to the Minnesota criteria and classified as MA-ECG or non-MA-ECG.Results A total number of 5364 subjects (2003 men,3361 women) were finally included in this analysis.(1) The standardized prevalence of MA-ECG was 7.3％ (7.0％ in men,7.7％ in women).In both genders,the age-specific prevalence of MA-ECG significantly increased with age (Ptrend＜0.01).The age-specific prevalence of MA-ECG in youths,middle aged and the elderly were 2.3％,7.7％,and 17.3％ in men,and 3.3％,8.8％ and 16.4％ in women,respectively (both Ptren＜0.01).(2) The three most common MA-ECG forms were arrhythmia (28.8％),bundle branch block (26.5％) and ST segment depression (20.0％) in men,while there appeared ST segment depression (44.6％),arrhythmia (23.0％) and combined MA-ECG (11.8％) in women.(3) Data from multivariate logistic regression analysis showed that other than age,coronary heart disease (CHD) was the only independent risk factor of MA-ECG in men,with its corresponding OR being 2.33-2.39; while in women,menopause (OR value1.72-1.85) and hypertension (OR value1.33-1.34) were main factors related to MA-ECG.Conclusion MA-ECG was prevalent in the middle aged and the elderly,with,arrhythmia and ST segment depression the most frequent forms of MA-ECG.Age,CHD and hypertension were the main risk factors of MA-ECG in the adults from Shanghai.