Changes of sperm chromatin in oligo-astheno-teratozoospermia syndrome patients after treated by integrated Chinese and Western medicine / 中华男科学杂志
National Journal of Andrology
; (12): 334-337, 2008.
Article
in Zh
| WPRIM
| ID: wpr-319257
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the changes of sperm chromatin in patients with oligo-astheno-teratozoospermia (OAT) syndrome after treated by integrated Chinese and Western medicine.</p><p><b>METHODS</b>Sixty patients with OAT syndrome were treated by integrated Chinese and Western medicine for 3 months. Their sperm samples were collected before and after the treatment, subjected to acridine orange staining and analyzed by fluorescent microscopy, flow cytometry and sperm routine detection.</p><p><b>RESULTS</b>Significant differences were shown in the master-group sperm signals (P < 0.01) and at and COMPalphat (P < 0.05) by flow cytometry, as well as in the green and the red groups (P < 0.05) by fluorescent microscopy before and after the treatment. Changes in sperm concentration, motility, vitality and deformity were noted after the treatment, with statistic difference between pre- and post-treatment (P < 0.05) except in forward sperm concentration.</p><p><b>CONCLUSION</b>Treatment by integrated Chinese and Western medicine can improve sperm chromatin in patients with OAT syndrome. Flow cytometry, along with fluorescent microscopy and sperm routine detection, plays an important role in the evaluation of male infertility therapy.</p>
Full text:
1
Index:
WPRIM
Main subject:
Oligospermia
/
Pathology
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Sperm Count
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Sperm Motility
/
Spermatozoa
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Therapeutics
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Chromatin
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Combined Modality Therapy
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Flow Cytometry
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Medicine, Chinese Traditional
Type of study:
Diagnostic_studies
Limits:
Adult
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Humans
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Male
Language:
Zh
Journal:
National Journal of Andrology
Year:
2008
Type:
Article