Insulin resistance model induced by dexamethasone in rats / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 98-100, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-319369
ABSTRACT
<p><b>AIM</b>To build a easy and reliable rat model of insulin resistance.</p><p><b>METHODS</b>Changes concerning sugar metabolism were observed in experimental rats injected intraperitoneally by different doses of dexamethasone.</p><p><b>RESULTS</b>The changes by dexamethasone in fasting blood insulin and insulin resistance prior to that of fasting blood glucose were dose and time dependent.</p><p><b>CONCLUSION</b>It was convenience to set up a insulin resistance model induced by dexamethasone in rats which would favor other related research.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
Time Factors
/
Blood
/
Blood Glucose
/
Insulin Resistance
/
Dexamethasone
/
Rats, Sprague-Dawley
/
Disease Models, Animal
/
Dose-Response Relationship, Drug
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS