Relation of intramyocardial collagen remodeling to the changes of myocardial systolic property and angiotensin II on the overtraining rats / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>To investigate the relation of intramyocardial collagen (IMC) remodeling to the changes of myocardial systolic property (MSP) and angiotensin II (Ang II) on the overtraining rats.</p><p><b>METHODS</b>Morphologic remodeling of IMC and changes of contents of IMC and Ang II in myocardium local and circulation, and MSP in SD rat overtraining models were observed and determined by RM-6200 polygraph, Beckman-42 automatic biochemistry analyser, and gamma automatic radio-immunity analyzer and S-570 scanning electron microscope under the conditions.</p><p><b>RESULTS</b>IMC forms a spatial three-dimensional network structure, consisting of collagenous fiber connection among myocardial bundles, cardiac muscle cell group, cardiac muscle cells, endocardium and capillary. There are some regularities in its interlacing.</p><p><b>CONCLUSION</b>Overtraining could lead to over hyperplasia of IMC in myocardial bundles, cardiac muscle cell group, cardiac muscle cell, endocardium and capillary, and serious injury of MLSP. The relation closes to remodeling of IMC and MSP and Ang II on the overtraining.</p>