Sulfogalactosylglycerolipid in spermatogenesis and fertilization / 中华男科学杂志
National Journal of Andrology
;
(12): 175-178, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-319521
ABSTRACT
Sulfogalactosylglycerolipid (SGG) is the main glycolipid in male mammalian germ cells, which is selectively and highly expressed in mammalian testes and helps form the lipid bilayer of cell membrane. In the process of spermatogenesis, SGG is involved in the meiosis of spermiocytes. Either deficiency or accumulation of SGG will lead to male infertility. SGG homeostasis in the testis is the premise of normal spermatogenesis. In the process of sperm-zona binding, SGG becomes a component of lipid raft and provides a platform for signal transduction. The SGG binding protein plays a role in sperm-egg recognition and membrane fusion. SGG has a great research value and application prospect in male reproduction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Sperm-Ovum Interactions
/
Spermatogenesis
/
Spermatozoa
/
Testis
/
Signal Transduction
/
Cell Membrane
/
Galactolipids
/
Infertility, Male
/
Lipid Bilayers
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2015
Type:
Article
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