Study on percutaneous absorption of xiaozheng zhitong cataplasm / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3907-3909, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-319681
ABSTRACT
<p><b>OBJECTIVE</b>To study the transdermal behavior of Xiaozheng Zhitong cataplasm in rats.</p><p><b>METHOD</b>With tetrahydropalmatine as the index, the Franz diffusion cell method was adopted for the experiment. Sample content was determined with HPLC.</p><p><b>RESULT</b>The transdermal permeability and the transmission rate of tetrahydropalmatine accumulated for 24 h were 20.20% and 0.744 1 microg x cm(-2) x h(-1), respectively.</p><p><b>CONCLUSION</b>The transdermal behaviors of Xiaozheng Zhitong cataplasm were ideal in conformity with the zero order kinetic model.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Permeability
/
Skin Absorption
/
Administration, Cutaneous
/
Drugs, Chinese Herbal
/
Pharmacokinetics
/
Chromatography, High Pressure Liquid
/
Rats, Wistar
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article
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