Toll-like receptors and their role in pathogenesis and vaccine study of cutaneous diseases / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 222-229, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-319805
ABSTRACT
Toll like receptor (TLR) can specifically recgnize pathogen-associated molecular patterns (PAMPs) and is considered as an important link between innate and adaptive immunity. It has been shown that TLR plays an important role in the pathogenesis and pathophysiology of a variety of skin diseases. Moreover, TLR agonists have exhibited promising therapeutic effects on the disease models and are expected to be novel vaccine adjuvants. Investigations of the underlying mechanism will give new insights into these diseases. This review will discuss the relationship between TLR and pathogenesis and management of some cutaneous diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Skin Diseases
/
Signal Transduction
/
Allergy and Immunology
/
Toll-Like Receptors
/
Adaptive Immunity
/
Immunity, Innate
/
Metabolism
Type of study:
Etiology study
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2011
Type:
Article
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