Recent advances in pharmacological intervention for prediabetes / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1565-1572, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-320041
ABSTRACT
Prediabetes is an abnormal condition between normal glucose metabolism and diabetes mellitus. Impaired glucose tolerance (IGT) is an indicator of high-risk state of prediabetes. Positive interventions of IGT, including life style changes and pharmacological intervention, can effectively postpone and reduce the development of prediabetes into type 2 diabetes mellitus, suggesting that IGT is a key point of diabetes prevention. Currently, pharmacological intervention for prediabetes is still at early stage. In this review, we summarizes recent clinical and preclinical studies on pharmacological intervention for prediabetes, and studies in the development of animal models with IGT and the application of new techniques. We also discuss the prospects of drugs for diabetes prevention, especially with the traditional Chinese medicine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prediabetic State
/
Drugs, Chinese Herbal
/
Glucose Intolerance
/
Therapeutic Uses
/
Diabetes Mellitus, Type 2
/
Disease Models, Animal
/
Drug Therapy
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2015
Type:
Article
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