A new indole derivative from endophyte Myrothecium roridum IFB-E091 in Artemisia annua / 药学学报
Acta Pharmaceutica Sinica
; (12): 1305-1308, 2015.
Article
in Zh
| WPRIM
| ID: wpr-320085
Responsible library:
WPRO
ABSTRACT
Three compounds were isolated from solid culture of endophyte Myrothecium roridum IFB-E091 in Artemisia annua. Their structures were determined as (S)-(-)-N-[2-(3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide (1), N-(4-hydroxyphenethyl)acetamide (2) and asperfumoid (3), in which compound 1 was a new indole derivative. In cytotoxicity assay, the compound 1 had no obvious inhibition activity in human hepatoma cell line SMMC-7721 and human cervical carcinoma cell line HeLa.
Full text:
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Index:
WPRIM
Main subject:
Chemistry
/
Artemisia annua
/
Cell Line, Tumor
/
Endophytes
/
Hypocreales
/
Indoles
/
Microbiology
Limits:
Humans
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2015
Type:
Article