Clinical findings and imaging features of 67 nasopharyngeal carcinoma patients with postradiation nasopharyngeal necrosis / 癌症
Chinese Journal of Cancer
;
(12): 533-538, 2013.
Article
in English
| WPRIM
| ID: wpr-320575
ABSTRACT
Postradiation nasopharyngeal necrosis is an important late effect of radiotherapy that affects prognosis in patients with nasopharyngeal carcinoma. In the present study, we reviewed the clinical and imaging features of 67 patients with pathologically diagnosed postradiation nasopharyngeal necrosis who were treated at Sun Yat-sen University Cancer Center between June 2006 and January 2010. Their clinical manifestations, endoscopic findings, and imaging features were analyzed. Early nasopharyngeal necrosis was limited to a local site in the nasopharyngeal region, and the tissue defect was not obvious, whereas deep parapharyngeal ulcer or signs of osteoradionecrosis in the basilar region was observed in serious cases. Those with osteoradionecrosis and/or exposed carotid artery had a high mortality. In conclusion, Postradiation nasopharyngeal necrosis has characteristic magnetic resonance imaging appearances, which associate well with clinical findings, but pathologic examination is essential to make the diagnosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoradionecrosis
/
Pathology
/
Radiation Effects
/
Radiation Injuries
/
Radiotherapy
/
Magnetic Resonance Imaging
/
Carcinoma
/
Nasopharynx
/
Nasopharyngeal Neoplasms
/
Diagnosis
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Journal of Cancer
Year:
2013
Type:
Article
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