Viral etiology and risk factors for severe community-acquired pneumonia in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 449-453, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-320623
ABSTRACT
<p><b>OBJECTIVE</b>To study the virus spectrum of severe community-acquired pneumonia (CAP) and risk factors for the disease in children.</p><p><b>METHODS</b>Respiratory secretion specimens were collected from 1096 children hospitalized with CAP from June 2007 to November 2008, including 100 cases of severe CAP. Respiratory viruses were detected by PCR, nest-PCR or RT-PCR. Clinical data on the children were analyzed by univariate and multivariate logistic regression analysis for examining risk factors for severe CAP.</p><p><b>RESULTS</b>Viral pathogens were isolated from 82 (82%) of the 100 cases with severe CAP. RSV was the most common (37%), followed by HBoV (25%) and HRV (18%). Mixed infection was noted in 32 cases (32%). The presence of underlying diseases (OR=6.623, P<0.01) and RSV infection (OR=1.672, P<0.05) were risk factors for severe CAP in children, while age was a protective factor (OR=0.475, P<0.01).</p><p><b>CONCLUSIONS</b>RSV is the most frequent viral pathogen in children with severe CAP. The presence of underlying diseases and RSV infection may be risk factors for severe CAP, while age is a protective factor.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia, Viral
/
Respiratory Syncytial Viruses
/
Virology
/
Logistic Models
/
Risk Factors
/
Community-Acquired Infections
/
Human bocavirus
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2012
Type:
Article
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