Changes of IgE and eosinophil in atopic dermatitis

ABSTRACT

The total serum IgE level and blood eosinophil count were evaluated in 44 adult patients with atopic dermatitis and were compared with 13 healthy controls for IgE level, and with 31 healthy controls for eosinophil count. It is found that both mean of IgE levels (X+/-SD=1129.86+/-984.54 IU/mL) and absolute number of eosinophils (X+/-SD = 0.857+/-0.736 G/L) were significantly elevated in comparison with control groups (p<0.001). There was closed correlation between IgE level, eosinophil count and severity of disease (r=0.60, 0.58 respectively with p<0.01). There was weak correlation between IgE level and eosinophil count with r = 0.22.