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Progress in regulation effect of aromatic refreshing traditional Chinese medicine on BBB permeability and its mechanism / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 949-954, 2014.
Article in Chinese | WPRIM | ID: wpr-321386
ABSTRACT
The blood-brain barrier (BBB) protects the brain against unwanted substances, while, at the same time, limits the transport of many drugs into the brain. Aromatic refreshing traditional Chinese medicine (TCM) can induce resuscitation and modify the permeability of BBB, promoting other drugs entering into the brain with brain protection effect. This paper mainly reviews the research progress in regulation effects and mechanism of usual aromatic refreshing TCM, such as borneol, moschus, styrax, benzoinum and Tatarinow Sweetflag Rhizome, on BBB permeability. To broaden the application of these drugs in modern pharmaceutics in the future, the relatively research should emphasis on combining aromatic refreshing TCM with new formulations and technologies in pharmaceutics, providing novel promising strategies for brain diseases therapy.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Permeability / Blood-Brain Barrier / Medicine, Chinese Traditional / Metabolism / Methods Type of study: Diagnostic study Limits: Animals / Humans Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Permeability / Blood-Brain Barrier / Medicine, Chinese Traditional / Metabolism / Methods Type of study: Diagnostic study Limits: Animals / Humans Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2014 Type: Article