Prenatal diagnosis of single umbilical artery: implications for chromosomal abnormalities and neonatal outcome / 南方医科大学学报
Journal of Southern Medical University
;
(12): 451-453, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-322025
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the implications of a prenatal diagnosis of single umbilical artery (SUA) for chromosomal abnormalities and neonatal outcomes.</p><p><b>METHODS</b>From January, 2008 to June, 2012, color Doppler ultrasound identified 44 fetuses with SUA. Prenatal diagnoses with amniocentesis or umbilical blood sampling were subsequently ordered for routine chromosome karyotyping and the newborns were followed up for assessing the neonatal outcomes.</p><p><b>RESULTS</b>Of all the 44 fetuses, 24 had uncomplicated SUA, and 20 had other concurrent abnormalities (including 8 with abnormal ultrasound soft indexes and 12 with chromosomal abnormalities). The two groups of fetuses showed significant differences in gestational weeks at delivery and incidence of chromosomal abnormalities but not in neonatal weight, placenta weight or APGAR score.</p><p><b>CONCLUSIONS</b>Fetuses with a prenatal diagnosis of SUA and other development abnormities need to undergo prenatal chromosomal examination. For fetuses with uncomplicated SUA, careful ultrasound examination is necessary to avoid missed diagnosis of potential congenital abnormalities.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pregnancy Trimester, Second
/
Pregnancy Trimester, Third
/
Congenital Abnormalities
/
Diagnostic Imaging
/
Ultrasonography, Prenatal
/
Chromosome Disorders
/
Single Umbilical Artery
/
Fetus
/
Genetics
/
Karyotyping
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article
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