Relationship between changes of serum soluble Fas levels and delayed encephalopathy after acute carbon monoxide poisoning / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>By explore the role of serum soluble Fas (sFas) in occurrence and progression of delayed encephalopathy after acute carbon monoxide poisoning (DEACMP).</p><p><b>METHODS</b>Enzyme-linked immunosorbent assay (ELISA) was used to detect serum sFas levels in 40 patients with DEACMP in acute stage and convalescent stage, with 36 healthy elderly subjects as the control group.</p><p><b>RESULTS</b>Serum sFas levels of the patients with DEACMP in both the acute and convalescent stages showed no significant difference from those in the control group (P=0.737 and 0.137, respectively), nor was any significant difference found between the patients in acute and exacerbation stages (P=0.059).</p><p><b>CONCLUSION</b>Serum sFas is not involved in the occurrence and progression of DEACMP.</p>