Diagnostic value of (18)F-FDG PET/CT for solitary nodular-type bronchoalveolar carcinoma / 南方医科大学学报
Journal of Southern Medical University
;
(12): 114-116, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-322103
ABSTRACT
<p><b>OBJECTIVE</b>To assess the value of (18)F-FDG PET/CT in the diagnosis of solitary nodular-type bronchoalveolar carcinoma (BAC).</p><p><b>METHODS</b>The clinical and radiographic data were analyzed retrospectively in 30 patients with pathologically confirmed solitary nodular-type BAC who underwent (18)F-FDG PET/CT examinations between August, 2005 and December, 2006. The morphological and radioactive findings of the lesions were reviewed, and the maximum standard uptake values (SUVmax) were measured. The diagnostic accuracy of PET, PET/CT, and HRCT were analyzed.</p><p><b>RESULTS</b>The (18)F-FDG SUV was markedly lower in BAC than in other well differentiated adenocarcinoma. In 19 of the BAC cases, PET showed a SUVmax of no less than 2.5, demonstrating positive changes. Of the total of 30 cases, 5 had ground glass opacity (GGO) changes, 3 exhibited mixed nodules with GGO changes around the lesions, and 22 cases presented with solid nodules. HRCT showed that BAC located often in the superior lobes of the bilateral lungs, mostly below the pleura in the surrounding lung field; the lesions were patchy or nodular with irregular shapes, showing lobulation in 22 cases, spiculation in 15 cases, pleural indentation in 21 cases, and vacuolar changes in 4 cases. The diagnostic accuracy of PET, PET/CT and HRCT for solitary nodular-type BAC was 36.67%, 93.33%, and 93.33%, respectively.</p><p><b>CONCLUSION</b>The SUVmax of BAC provides only limited value for defining the nature of the lesions, but can serve as a general reference for assessing the disease activity. PET/CT, which allows both functional and imaging assessment, can be a valuable modality to reduce the misdiagnosis rate of BAC.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Diagnostic Imaging
/
Tomography, X-Ray Computed
/
Retrospective Studies
/
Adenocarcinoma, Bronchiolo-Alveolar
/
Fluorodeoxyglucose F18
/
Positron-Emission Tomography
/
Lung Neoplasms
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article
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