Efficacy of Prophylactic Antibiotics in Dermatological Punch biopsy / 대한피부과학회지
Korean Journal of Dermatology
;
: 724-727, 2004.
Article
in Korean
| WPRIM
| ID: wpr-32248
ABSTRACT
BACKGROUND:
Punch biopsy has been used frequently as a diagnostic method in dermatologic field. However dermatologist administrated antibiotics is routine for the prevention of wound infection.OBJECTIVE:
The purpose of this study was to evaluate the efficacy of prophylactic antibiotics in punch biopsy.METHODS:
Four hundred and one patients undergoing punch biopsy were studied prospectively. Patients were randomly split in to two groups group I received prophylactic antibiotics after punch biopsy (197 patients), group II didn't receive any antibiotic after punch biopsy (204 patients). Wound infection was defined as a condition of erythema, edema, and pain or purulent discharge.RESULTS:
Patients demographics and skin disease were similar between two groups. Biopsy site were infected in 3 patients of group I and 5 patients of groups II. Staphylococcus aureus, Staphylococcus epidermidis and Bacteroides fragilis were isolated from the infected biopsy site. There was no significant difference of infection rate between two groups.CONCLUSION:
This result suggests that the routine use of prophylactic antibiotics after skin punch biopsy is unnecessary.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Skin Diseases
/
Staphylococcus aureus
/
Staphylococcus epidermidis
/
Bacteroides fragilis
/
Wound Infection
/
Biopsy
/
Demography
/
Prospective Studies
/
Edema
Type of study:
Observational study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2004
Type:
Article
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