Investigation of the mechanism of genitofemoral nerve in the contralateral testes damage of unilateral cryptorchid rats / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVES</b>To investigate the mechanism of genitofemoral nerve in the contralateral testes damage of unilateral cryptorchid rats.</p><p><b>METHODS</b>After unilateral cryptorchid rat model (21-day) was made and the ipsilateral genitofemoral nerve was divided, the germ cells apoptosis and the concentrations of lactate of contralateral testes were detected and compared after 120 days.</p><p><b>RESULTS</b>After the ipsilateral genitofemoral nerve was divided, the germ cells apoptosis and the lactate levels of the contralateral testes were all decreased from (17.28 +/- 1.36)% to (5.76 +/- 0.76)% and (2.19 +/- 0.24) mmol/L to (1.70 +/- 0.31) mmol/L, respectively.</p><p><b>CONCLUSIONS</b>The damage pathway of the contralateral testes of unilateral cryptorchidism probably related to the apoptosis of the germ cells which caused by the reflex decrease of the contralateral testicular blood flow via the transmissions of genitofemoral nerve.</p>