Distributions of high-sensitivity C-reactive protein and its association with metabolic syndrome in population aged 45-74 in Beijing / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 1155-1158, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-322836
ABSTRACT
<p><b>OBJECTIVE</b>To describe the distributions of high-sensitivity C-reactive protein (hs-CRP) and its association with metabolic syndrome (MS) in population aged 45-74 in Beijing.</p><p><b>METHODS</b>A population-based cross-sectional survey was conducted in Beijing during 2002-2004 and the component of MS and plasma hs-CRP concentration were assessed. Analysis was performed in a total of 1544 subjects with completed information. Metabolic syndrome was defined according to the updated National Cholesterol Education Program Adult Treatment Panel III criteria for Asian Americans.</p><p><b>RESULTS</b>The median and geometric mean concentrations of hs-CRP among our study population were 1.00 mg/L and 0.79 mg/L, respectively, hs-CRP level showed an upward trend with increased age (P<0.05) but no statistically significant difference of hs-CRP levels between genders was observed (P>0.05). The prevalence of MS progressively increased with elevated hs-CRP quartiles (P<0.01). The prevalence rates of hypertension and central obesity were substantially higher in the highest quartile of hs-CRP levels than those in the lowest quartile. In a univariate logistic regression analysis, the risk for MS was higher in the highest quartile of hs-CRP than that in the lowest quartile. After adjusting for age, sex, smoking and drinking, the highest quartile of hs-CRP was found to be independently associated with each component of MS and 6.35-fold increased risk of MS.</p><p><b>CONCLUSION</b>The hs-CRP level appeared to be increased with age and correlated to all the components of MS.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
C-Reactive Protein
/
Cardiovascular Diseases
/
Logistic Models
/
China
/
Metabolic Syndrome
/
Metabolism
Type of study:
Diagnostic study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2007
Type:
Article
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