Mass spectrometry technology and its application in analysis of biological samples / 药学学报
Acta Pharmaceutica Sinica
;
(12): 158-162, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-323065
ABSTRACT
With the excellent merits of wide analytical range, high sensitivity, small sample size, fast analysis speed, good repeatability, simple operation, low mobile phase consumption, as well as its capability of simultaneous isolation and identification, etc, mass spectrometry techniques have become widely used in the area of environmental science, energy chemical industry, biological medicine, and so on. This article reviews the application of mass spectrometry technology in biological sample analysis in the latest three years with the focus on the new applications in pharmacokinetics and bioequivalence, toxicokinetics, pharmacokinetic-pharmacodynamic, population pharmacokinetics, identification and fragmentation pathways of drugs and their metabolites and metabonomics to provide references for further study of biological sample analysis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Mass Spectrometry
/
Pharmacokinetics
/
Pharmaceutical Preparations
/
Therapeutic Equivalency
/
Chemistry
/
Drug-Related Side Effects and Adverse Reactions
/
Metabolomics
/
Methods
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2012
Type:
Article
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