Regulatory mechanism underlying pathogen biofilm formation and potential drug targets / 药学学报
Acta Pharmaceutica Sinica
;
(12): 135-143, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-323067
ABSTRACT
Bacterial communities usually develop biofilms abound in nature niche. The development of biofilm is a highly dynamic and complex process coordinated by multiple mechanisms, of which two-component system and quorum sensing are two well-defined systems. Biofilm is involved in the virulence of many pathogens. Therefore, targeting the key factors involved in the biofilm formation represents a novel and promising avenue for developing better antibiotics.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bacteria
/
Bacterial Proteins
/
Signal Transduction
/
Gene Expression Regulation, Bacterial
/
Drug Delivery Systems
/
Biofilms
/
Quorum Sensing
/
Acyl-Butyrolactones
/
Genetics
/
Homoserine
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS