Study on the progress of the mechanism of TGF-beta in the scarring and the effect of TCM / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 161-163, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-323115
ABSTRACT
Transforming growth factor (TGF-beta) plays a central role in wound healing and scarring. TGF-beta is a member of cytokine family, involving cell proliferation, migration, differentiation and apoptosis, which subsequently trigger extracellular matrix (ECM) deposite and collagen overproduction. A number of regulators of TGF-beta expression bave been identified, including Decorin CTGF, etc. TCM can reduced later scarring, and it accelerates wound healing. TCM can reduce the expression of TGF-beta, resistance of fibrosis, so that lighten the development of scar. This article reviewed the mechanism of TGF-beta in the scarring and TCM can decrease the development of scar effected by TGF-beta.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Fibrosis
/
Gene Expression Regulation
/
Transforming Growth Factor beta
/
Cicatrix
/
Drug Therapy
/
Medicine, Chinese Traditional
/
Metabolism
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2008
Type:
Article
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