Feasibility of proton magnetic resonance spectroscopy of the myocardium in vivo / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the feasibility of proton magnetic resonance spectroscopy ((1)H-MRS) of the myocardium in vivo.</p><p><b>METHODS</b>A total of 100 volunteers were examined with 1H-MRS scan using a 1.5T MR scanner, and the magnetic resonance spectra were analyzed.</p><p><b>RESULTS</b>All the volunteers completed the examinations, and the spectral peaks were identified with the chemical shifts of water (4.7 ppm), choline (3.2 ppm), creatine (3.0 ppm), and triglyceride (0.9-1.6 ppm), whose presentation ratios were 100%, 86%, 90%, and 98%, respectively. In 86 cases the spectra showed all the chemical shifts. The myocardial metabolite contents were expressed as the ratio of metabolites to water (%), and the contents of choline, creatine, and triglyceride were 1.94%, 1.95%, and 9.41%, respectively.</p><p><b>CONCLUSION</b>(1)H-MRS can be used in detecting the metabolic products of myocardium in vivo.</p>