The changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 375-376, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-324259
ABSTRACT
<p><b>OBJECTIVE</b>To explore the changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning.</p><p><b>METHODS</b>When the patients were admitted or on the secondary day, the percentages of total T-cell lymphocyte subsets (CD(3)(+)CD(19)(-)), CD(4)(+)T cells (CD(3)(+)CD(4)(+)), CD(8)(+)T cells (CD(3)(+)CD(8)(+)), B cells (CD(3)(-)CD(19)(+)) and NK cells (CD(3)(-)CD(16)(+)CD(56)(+)), and the ration of CD(4)(+)/CD(8)(+) in 37 cases with acute hydrogen chloride gas poisoning and 49 healthy controls were detected with flow cytometer.</p><p><b>RESULTS</b>The total T-cell percentage and total CD(4)(+)T cell percentage in 37 cases were significantly lower than those in 47 controls (P < 0.05). The percentages of NK cells and B lymphocytes in 37 cases significantly increased, as compared with controls (P < 0.05). The ration of CD(4)(+)/CD(8)(+) in 37 cases significantly decreased, as compared with controls (P < 0.05).</p><p><b>CONCLUSION</b>The lymphocyte subsets in the patients with acute hydrogen chloride gas poisoning changed, which could influence the immune function of patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Poisoning
/
Blood
/
Case-Control Studies
/
Lymphocyte Subsets
/
Lymphocyte Count
/
Cell Biology
/
Gas Poisoning
/
Hydrochloric Acid
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Year:
2012
Type:
Article
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