Chemical constituents in unsaponifiable matter from seeds of Trichosanthes hupehensis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of unsaponifiable matter from the seed oil of Trichosanthes hupehensis.</p><p><b>METHOD</b>The fatty oil from the seeds of T. hupehensis was extracted with petroleum ether. The saponification was carried out with potassium hydroxide. The unsaponifiable matter was isolated and purified by silica gel column chromatography. Their structures were elucidated by means of MS, IR, UV, and 1H-NMR.</p><p><b>RESULT</b>Karounidiol, isokarounidiol, 5-dehydrokarounidiol, 7-oxodihydrokarounidiol, stigmast-7-en-3beta-ol, stigmast-7, 22-dien-3beta-ol, 10alpha-Cucurbitadienol, beta-sitosterol, stigmast-7, 22-dien-3beta-O-beta-D-glucoside were elucidated.</p><p><b>CONCLUSION</b>All of these compounds were found in this plant for the first time.</p>