Study on extraction and drying of Ligusticum chuanxiong in Gan-ning Granule / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To find out the optimum extract process for Ligusticum chuanxiong in Gan-ning Granule, and studyed the methods of concentration and dry for the extract.</p><p><b>METHOD</b>With the yield of ferulic acid as the assessment index, to optimize the 80% alcohol totalling, extracting times and circumfluence time for extract process by the orthogonal design, to optimize the inlet-air temperature, feed speed and density of feed for spry drying by the orthogonal design.</p><p><b>RESULT</b>The optimum procedure was the ferulic acid were extracted for 1 hour with 3 times of 80% alcohol. While extracting times effected it most porminently. The optimal processing conditions of spry drying were inlet-air temperature 120 degrees C, feed speed 8.5 mL x min(-1) and density of feed 1.15, While feed speed effected it most porminently.</p><p><b>CONCLUSION</b>The experimental results provide the basis for the extraction process and drying process of the ferulic acid in ligusticum chuanxiong.</p>