Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the stability of curcumin, demethoxycurcumin and bisdemethoxycurcumin in different buffer solution.</p><p><b>METHOD</b>To determine concentration of curcumin by HPLC when added curcumin, demethoxycurcumin and bisdemethoxycurcumin into the buffer solution the equation of degradation was established.</p><p><b>RESULT</b>The sequence of stability are bisdemethoxycurcumin > or = demethoxycurcumin > or =curcumin at the same condition.</p><p><b>CONCLUSION</b>The demethoxycurcumin can stabilize curcumin more strong than the others. The demethoxycurcumin is a nature stabilizing agent for curcumin.</p>