Analysis of the risk factors of community-acquired pneumonia in patients with primary Sjogren's syndrome / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the risk factors of community-acquired pneumonia (CAP) in patients with primary Sjogren's syndrome (pSS).</p><p><b>METHODS</b>The clinical data were collected from 121 inpatients with pSS and univariate analysis and logistic regression were conducted to analyze the risk factors of CAP.</p><p><b>RESULTS</b>The incidence of CAP in the 121 patients with pSS was 27.3%. Age, disease course, low while blood cells, low complement levels, liver and kidney dysfunction, low albumin, hyperglobulinaemia, renal tubule acidosis, interstitial lung disease (ILD) and immunosuppressive agents were closely related to CAP in these patients. Logistic regression analysis identified ILD, low complement levels and hyperglobulinemia as the risk factors for CAP in patients with pSS.</p><p><b>CONCLUSION</b>Vigorous control of pSS and minimizing the risk factors may prove effective to lower the incidence of CAP in patients with pSS.</p>