Relation between clinical detection rates of the novel influenza virus A/H1N1 RNA in confirmed patients in Guangzhou and the disease course / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2313-2315, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-325121
ABSTRACT
<p><b>OBJECTIVE</b>To study the relation of the detection rates of the novel influenza virus A/H1N1 RNA in clinically confirmed patients in the 2009 pandemic with the age distribution of the patients and the disease course.</p><p><b>METHODS</b>A total of 151 clinical patients with H1N1 infection were enrolled in this study, from whom 833 dynamic throat swab samples were obtained for detecting the H1N1 RNA using real-time PCR. A statistical analysis of the age distribution was performed among the patients with different disease courses. Chi-square for trend test was used to study the correlation between the detection rates of H1N1 RNA and the time of disease onset.</p><p><b>RESULTS</b>The majority of patients were young with their ages ranging from 10 to 20 years (57.26%) and 20 to 30 years (22.18%). Chi-square for trend test revealed that the positivity rates of the throat swabs in the patients decreased with the prolongation of the disease course (chi(2)=9.784, P=0.002).</p><p><b>CONCLUSION</b>Most of the H1N1 patients are young within the age range of 10-30 years, and the longest disease course can exceed 10 days. The positivity rates of throat swabs from the H1N1 patients decreases with the prolongation of the disease course.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharynx
/
Virology
/
RNA, Viral
/
China
/
Epidemiology
/
Age Factors
/
Reverse Transcriptase Polymerase Chain Reaction
/
Influenza, Human
/
Influenza A Virus, H1N1 Subtype
/
Genetics
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2009
Type:
Article
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