Efficacy of cellulose on functional constipation / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 182-184, 2009.
Article
in Zh
| WPRIM
| ID: wpr-326531
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To assess the clinical efficacy and safety of cellulose on functional constipation.</p><p><b>METHODS</b>A prospective, self-controlled, multicenter clinical trial of cellulose was conducted for 2 weeks in 240 patients with functional constipation according to the Rome III( criteria. Symptoms and characters of feces before and after the treatment were observed and evaluated according to a score scheme.</p><p><b>RESULTS</b>In the 240 patients, the frequencies of defecation increased and the characters of feces was improved significantly after 2-week treatment. There were no adverse reactions observed throughout the clinical trial. The total efficacy was 82.1% at day 7 and 90.7% at day 14. The satisfactory rate of doctors was 83.8% and of patients was 83.8%.</p><p><b>CONCLUSION</b>Cellulose is effective and safe in the treatment of chronic functional constipation.</p>
Full text:
1
Index:
WPRIM
Main subject:
Cellulose
/
Prospective Studies
/
Treatment Outcome
/
Constipation
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Therapeutic Uses
/
Drug Therapy
Type of study:
Clinical_trials
/
Observational_studies
Limits:
Adolescent
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Adult
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Aged
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Female
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Humans
/
Male
Language:
Zh
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2009
Type:
Article