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Clinical analysis of rectal neuroendocrine carcinoma:a report of 16 cases / 中华胃肠外科杂志
Article in Zh | WPRIM | ID: wpr-326534
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical data and surgical treatment strategy of rectal neuroendocrine carcinoma (NEC).</p><p><b>METHODS</b>Sixteen cases of rectal NEC and 222 cases of rectal carcinomas receiving surgical treatment in Beijing Cancer Hospital from 2003 to 2007, were analyzed retrospectively.</p><p><b>RESULTS</b>Among the 16 rectal NEC patients, 4(25%) received Miles surgery, 7(43.8%) Dixon surgery, 2 combined multiple organ resection and 3 local resection. Lymph note metastases occurred in 11 cases(68.8%) and distant metastases in 7 cases (43.8%). Among the 222 rectal carcinoma patients, 43(19.4%) received Miles surgery, 152(68.5%) Dixon surgery, 12 palliative operation, 6 colostomy and 9 just received laparotomy. Lymph note metastases occurred in 125 cases (56.3%). In rectal NEC group, postoperative 1-, 2- and 3-year survival rates were 62.5%, 25.0% and 0.63% respectively, which were significantly lower than 83.1%, 61.7% and 46.1% in rectal carcinoma group(all P<0.01).</p><p><b>CONCLUSIONS</b>Rectal NEC is a rare disease. More vascular invasion, lymph node and distant organ metastases are found in rectal NEC than rectal carcinoma, and the prognosis of rectal NEC is worse than rectal cancer.</p>
Subject(s)
Full text: 1 Index: WPRIM Main subject: Pathology / Prognosis / Rectal Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Chemotherapy, Adjuvant / Carcinoma, Neuroendocrine / Drug Therapy / Neoplasm Staging Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male Language: Zh Journal: Chinese Journal of Gastrointestinal Surgery Year: 2009 Type: Article
Full text: 1 Index: WPRIM Main subject: Pathology / Prognosis / Rectal Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Chemotherapy, Adjuvant / Carcinoma, Neuroendocrine / Drug Therapy / Neoplasm Staging Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male Language: Zh Journal: Chinese Journal of Gastrointestinal Surgery Year: 2009 Type: Article