Clinical analysis of rectal neuroendocrine carcinoma:a report of 16 cases / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 170-173, 2009.
Article
in Zh
| WPRIM
| ID: wpr-326534
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical data and surgical treatment strategy of rectal neuroendocrine carcinoma (NEC).</p><p><b>METHODS</b>Sixteen cases of rectal NEC and 222 cases of rectal carcinomas receiving surgical treatment in Beijing Cancer Hospital from 2003 to 2007, were analyzed retrospectively.</p><p><b>RESULTS</b>Among the 16 rectal NEC patients, 4(25%) received Miles surgery, 7(43.8%) Dixon surgery, 2 combined multiple organ resection and 3 local resection. Lymph note metastases occurred in 11 cases(68.8%) and distant metastases in 7 cases (43.8%). Among the 222 rectal carcinoma patients, 43(19.4%) received Miles surgery, 152(68.5%) Dixon surgery, 12 palliative operation, 6 colostomy and 9 just received laparotomy. Lymph note metastases occurred in 125 cases (56.3%). In rectal NEC group, postoperative 1-, 2- and 3-year survival rates were 62.5%, 25.0% and 0.63% respectively, which were significantly lower than 83.1%, 61.7% and 46.1% in rectal carcinoma group(all P<0.01).</p><p><b>CONCLUSIONS</b>Rectal NEC is a rare disease. More vascular invasion, lymph node and distant organ metastases are found in rectal NEC than rectal carcinoma, and the prognosis of rectal NEC is worse than rectal cancer.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Prognosis
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Rectal Neoplasms
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General Surgery
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Survival Rate
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Retrospective Studies
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Chemotherapy, Adjuvant
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Carcinoma, Neuroendocrine
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Drug Therapy
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Neoplasm Staging
Type of study:
Observational_studies
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Prognostic_studies
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2009
Type:
Article