Effect of safflower injection on cardiac energy charge and anti-apoptosis gene bcl-2 in rats' heart / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 442-444, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-326727
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of safflower injection (SI) in protecting heart, and on energy charge and anti-apoptosis gen bcl-2 in cardiac tissue.</p><p><b>METHODS</b>Rats' Langendorff isolated heart infused model was used in the experiment to study the effect of SI by measuring the cardiac function, energy charge and bcl-2 expression of the cultured heart in the modified Euro-Collins (mEC) heart preserving liquid with or without addition of SI.</p><p><b>RESULTS</b>As compared with the control, SI showed the effects of improving functions of cardiac contraction and dilation, increasing coronary blood flow, and strengthening the bcl-2 protein expression.</p><p><b>CONCLUSION</b>SI has excellent effect in protecting heart.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Physiology
/
In Vitro Techniques
/
Drugs, Chinese Herbal
/
Random Allocation
/
Chemistry
/
Ventricular Function, Left
/
Rats, Wistar
/
Apoptosis
/
Proto-Oncogene Proteins c-bcl-2
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2004
Type:
Article
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