Effect of Runing II on expression of vascular endothelial growth factor in transplanted tumor of mammary cancer MA-891 in TA2 mice / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 251-253, 2004.
Article
in Zh
| WPRIM
| ID: wpr-326780
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of Runing II on expression of vascular endothelial growth factor (VEGF) in transplanted tumor of mammary cancer MA-891 in TA2 mice.</p><p><b>METHODS</b>The MA-981 mice mammary cancer cell cultivated in vivo was inoculated into the right axilla subcutaneously of TA2 mice to establish the transplanted tumor model, which were treated with Runing II.</p><p><b>RESULTS</b>Runing II could inhibit the growth of transplanted tumor and the occurrence of lung metastasis (P < 0.05), reduce the expression of VEGF protein and mRNA in tumor tissue (P < 0.05).</p><p><b>CONCLUSION</b>Runing II could reduce the expression of VEGF protein and mRNA, hence to inhibit the growth of tumor and lung metastasis.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
RNA, Messenger
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Drugs, Chinese Herbal
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Reverse Transcriptase Polymerase Chain Reaction
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Vascular Endothelial Growth Factor A
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Genetics
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Mammary Neoplasms, Experimental
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Metabolism
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Neoplasm Transplantation
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Antineoplastic Agents, Phytogenic
Type of study:
Prognostic_studies
Limits:
Animals
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2004
Type:
Article