Using chemical methods to crosslink xenogeneic heart valves: the progress of bioprosthetic heart valves / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 735-737, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-326995
ABSTRACT
Glutaraldehyde clinically is the most commonly accepted crosslinking reagent for bioprosthetic valves preparation. Glutaraldehyde-treated tissue is stable against chemical and enzymatic degradation; however, its calcification and cytotoxicity are severe. Dye-mediated photooxidation is an alternative tissue preservation method that oxidizes the protein with visible light in the presence of a suitable photosensitizer. This article reviews chemical mechanism, research progress, clinical applications future development of these two methods.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Photochemistry
/
Bioprosthesis
/
Calcinosis
/
Heart Valve Prosthesis
/
Glutaral
/
Heart Valve Prosthesis Implantation
/
Cross-Linking Reagents
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2003
Type:
Article
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