Clinical observation on treatment of infantile rotavirus enteritis by umbilical application of lunxieting paste / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 1275-1278, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-327453
ABSTRACT
<p><b>OBJECTIVE</b>To observe the clinical effect of umbilical application with Lunxieting Paste (LXT) for the treatment of infantile rotavirus enteritis (IRE).</p><p><b>METHODS</b>One hundred and ninety infants with IRE were randomly assigned into three groups, 55 in Group A, 60 in Group B and 75 in Group C. All were treated with conventional therapy, mainly the dehydration and acidosis correcting, rehydration salt and antiviral therapy; but to patients in Groups B and C, an additional medication of Smecta 1.5 g, thrice a day. for infants below 1 year and 3 g, thrice a day. for those between 1-2 years old, by orally taken with 0.05 L of warm water and umbilical application with LXT (one dose per day, containing 6.0 g of crude drug) was given respectively.</p><p><b>RESULTS</b>The total effective rate was 69.1% in Group A, 75% in Group B and 92% in Group C, respectively, showing significant difference (P<0.05) in comparing Group C with Groups A and B. Moreover, serum levels of TNF-alpha were decreased and IFN-gamma increased in Group C after treatment, all showed statistical significance as compared with those in the other two groups (P<0.05). No significant adverse reactions were observed in all patients.</p><p><b>CONCLUSION</b>Umbilical application of LXT could effectively alleviate the diarrhea symptom in IRE patients, accelerate the negative inversion of rotavirus, and reduce the injury of intestinal membrane, showing a therapeutic efficacy more effective and quicker than that of conventional treatment with more convenience for use.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rotavirus Infections
/
Umbilicus
/
Virology
/
Administration, Cutaneous
/
Drugs, Chinese Herbal
/
Combined Modality Therapy
/
Diarrhea, Infantile
/
Drug Therapy
/
Enteritis
/
Phytotherapy
Limits:
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2010
Type:
Article
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